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Aromex containing Exemestane act as steroidal inhibitors of the enzyme aromatase, which controls the conversion of testosterone to estrone (E1) and androstenedione to estradiol (E2). This type of inhibition by Exemestane obstructs the synthesis of estrogen hormone in postmenopausal women who are diagnosed with breast cancer.
Aromex is prescribed as oral therapy for breast tumours which are dependent on estrogen for their growth and survival in the body and in tumours where treatment with other anti-cancer drugs such as Tamoxifen for two-three years has failed.
You should use Aromex exactly as recommended by your doctor. Your doctor may suggest a dosage of Aromex depending on your medical requirement, body weight, other medical conditions, and current medications. Aromex should be taken once a day with a glass of water, after a meal to avoid indigestion problems. Try to maintain a regular schedule for the medication such that you take Aromex at the same time every day, to get the maximum benefit of the medication.
Doctors usually recommend a dosage of a single Aromex once daily after a meal. Your doctor may alter the dosage of Aromex and dosage period depending on your response to treatment. The treatment with Aromex can be continued for a period of five years. You may need to monitor your health through frequent blood tests during the course of Aromex.
The following side effects have been reported during the course of treatment with Aromex: Cardiovascular System: - chest pain or tightness in the chest, increased blood pressure, blood clots, heart attack, stroke. Central Nervous System: - headache, confusion, nausea, insomnia, mental depression, anxiety, dizziness. Eye and ENT: - problems with vision, speech, or balance, sore throat, runny nose. Gastrointestinal System: - constipation, indigestion, diarrhoea, vomiting. Genitourinary System: - difficult, burning, or painful urination, frequent urge to urinate, vaginal bleeding, dark urine. Musculoskeletal System: - new or unusual bone pain, swelling of hands or feet, joint pain, lower back or side pain, osteoporosis. Respiratory System: - shortness of breath with mild exertion, cough. Hypersensitivity: - hives; difficult breathing; swelling of face, lips, tongue, or throat; fever; wheezing.
General: - sudden numbness, weakness, hot flashes, increased appetite, loss of appetite, oedema of the extremities, increased sweating, general discomfort, hair loss, decreased sense of touch, burning, tingling, or prickly sensations, yellowing eyes/skin, carpal tunnel syndrome, weight gain.
Inform your doctor immediately if you experience any of these side effects. This is not a comprehensive list of all the possible side effects of Aromex. If you develop any other medical conditions during the course of treatment with Aromex, please consult your doctor immediately.